The Science

1. Why Sleep is Important

"We no longer have to ask what sleep is good for. Instead we are forced to wonder whether there are any biological functions that do not benefit by a good night's sleep. So far the results of thousands of studies insist that no, there aren't."

Matthew Walker, Why We Sleep [1]

Now, more than ever, as a virus continues to sweep across the globe we must keep our immunity up and our general health in good order. One of the most important things that we can do to contribute to this is sleep. 

Sleep is the bedrock to our mental and physical health. Sleep recalibrates, cleanses and restores our minds and bodies each night. It is our daily reset to prepare us for a productive next day. Sleep reorganises the brain - shifting relevant facts and memories into our long term storage, removing unnecessary information to refresh our capacity for new learning and cleansing the “metabolic refuse left by our daily neural activity" [2]. Sleep tempers us - it controls our emotional state and prevents irrational reactions [3]. Sleep protects us from getting sick - every bodily function and system is impacted, negatively, by not getting enough good sleep [4]. 

Despite this, the majority of us don't get enough sleep or lack the sleep quality needed to support and maintain good health. In fact, the World Health Organization has recently declared a sleep loss epidemic in developing countries and have correlated this to increased rates of physical disease and mental illness [5].

Thankfully, we are now beginning to recognise the importance of sleep to living a long, healthy and happy life. Hopefully our Sleep Capsules can give you a helping hand here!

2. How our Sleep Capsules Work

Our Sleep Capsules are packed full of the building blocks your body already uses to fall asleep naturally. This means they don't knock you out or leave you feeling groggy the next day, but work gently with your body to lull you off to sleep and enhance your natural sleep processes throughout the night. Think of it as a daily vitamin, but for sleep!

We have worked with laboratory professionals at one of the UK's largest supplement manufacturers to develop our formula. With them, we have designed our Sleep Capsules to contain all the best ingredients needed to help you drift off, sleep better and dream bigger! But, rightly so, and especially when it comes to sleep, you want to know exactly what you are putting into our bodies. So, here is a rundown of all the ingredients we've used and why each is so important to your sleep. 

Core Ingredients:

 L-Theanine

L-Theanine is an amino acid found in green tea. Studies suggest L-Theanine helps relaxation and sleep in two core ways: firstly, by helping to increase levels of production of GABA, serotonin and dopamine which are three of the brain’s core neurotransmitters connected with mood regulation; and, secondly, by stimulating the brain’s release of alpha waves during REM sleep which is believed to enhance relaxation, focus and creativity [6],[7].

Griffonia Seeds

Griffonia Seeds are produced by a West African shrub called Griffonia Simplicifolia and are rich in in 5-HTP. 5-HTP helps the body produce serotonin which, in turn, can be converted into the hormone melatonin that regulates the body’s sleep-wake cycle (which is also sometimes referred to as the body's circadian rhythm) [8].

 L-Tryptophan

L-Tryptophan is an amino acid commonly found in nuts and seeds and is the building block of 5-HTP and a pre-cursor to serotonin and melatonin production. Studies suggest that combining 5-HTP [9] with sources of GABA (such as L-Theanine) can have a synergistic effect on sleep quantity and quality [10].

 Montmorency Cherry

Montmorency Cherry comes from a Southwest Asian tree called Prunus Cerasus. Studies have linked Montmorency Cherry with two important qualities: firstly, reducing muscle tension and inflammation [11]; and, secondly, promoting melatonin production [12]. 

 Magnesium

Magnesium is one of the most important minerals in the human body. It’s involved in more than 600 internal biochemical reactions from energy creation, to protein formation, muscle movements to nervous system regulations. It’s also been linked with muscle relaxation, reducing low moods [13] and relieving light / restless sleep patterns by activating the body's parasympathetic nervous system [14] and helping to regulate the body's sleep-wake cycle [15]. 

The Trio of Relaxing Herbs

Lemon Balm Chamomile  Lavender

Lavender, Lemon Balm and Chamomile are all herbs with a long history of therapeutic uses. Each has been connected with their calming and relieving properties [16,17,18] and in turn their ability to help us fall asleep. 

B Vitamin Complex 

 B Vitamins

B Vitamins are the building blocks of a healthy body [19]. From body and cell metabolism to new blood cell creation and brain functioning they play a vital role in maintaining our general good health and wellbeing. Our sleep supplements contain 4 of them: Vitamin B3,(Nicotinamide), Vitamin B5 (D-Calcium Pantothenate), Vitamin B6 (Pyridoxine Hydrochloride), Vitamin B12 (Cyanocobalamin). 

Other ingredients explained:

HydroxypropylMethylCellulose is the vegetable capsule shell which houses our ingredients. 

Microcrystaline Cellulose & Dicalcium Phosphate are vegan bulking agents used improve the flow of our ingredients through your digestive system and to mitigate against ingredient clumps forming during the production of our capsules.

Magnesium Stearate & Silicon Dioxide are anti-caking agents to ensure the ingredients equally bind and, once again, do not clump during the production our capsules. Silicon Dioxide is found naturally in many plants such as green vegetables and is a natural compound made of two of the earth’s most abundant materials: silicon (Si) and oxygen (O2). 

Timing

These are not sleeping pills so they will not immediately knock you out. Instead our Capsules work with your body's natural processes, this means it will take a bit of time to calibrate and optimise results. Like most supplements you should start to see an improvement within 2-3 weeks.

Our Sleep Capsules aren't a silver bullet so shouldn't replace a healthy lifestyle. You will still feel the effects of partying until 4am (when that time comes again). 

3. How to take our Sleep Capsules?

For the first night, take one capsule with water an hour before bed. From the second night on, increase to two capsules nightly and make it part of your bedtime routine. Don’t chew and do not exceed the recommended dose!

4. Safety

Our sleep capsules are a food supplement. Please do not use if you are taking any medicine for sleep or are allergic to any of the ingredients listed. This product is suitable for adults over 18 only. Do not exceed recommended dose. Please speak to your doctor before taking if you are pregnant, breastfeeding, under medical supervision or suffer from food allergies. If you feel sleepy, do not drive or operate machines. Store in a cool, dry place. Keep out of sight and reach of children.

References:

[1], [2], [3], [4], [5] Walker, Matthew (2017), Why We Sleep

[6] Mason, Russ (2004). 200 mg of Zen: L-theanine Boosts Alpha Waves, Promotes Alert Relaxation. Alternative and Complementary Therapies, 7(2): 91-5. Retrieved from: http://online.liebertpub.com/doi/abs/10.1089/10762800151125092

[7] https://pubmed.ncbi.nlm.nih.gov/17182482/#:~:text=L%2Dtheanine%20has%20been%20historically,AMPA%2C%20Kainate%20and%20NMDA%20receptors.

[8] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646716/

[9] https://pubmed.ncbi.nlm.nih.gov/23388477/

[10] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974066/

[11] https://pubmed.ncbi.nlm.nih.gov/19883392/

[12] https://pubmed.ncbi.nlm.nih.gov/22038497/

[13] https://pubmed.ncbi.nlm.nih.gov/25540137/

[14] https://pubmed.ncbi.nlm.nih.gov/16542786/

[15] https://pubmed.ncbi.nlm.nih.gov/8232845/

[16] https://pubmed.ncbi.nlm.nih.gov/27933574/

[17] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910806/

[18] https://pubmed.ncbi.nlm.nih.gov/15272110/

[19] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710842/

[20] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612440/#B29

[21] https://www.sciencedirect.com/science/article/abs/pii/S0944711306000250?via%3Dihub

[22] https://pubmed.ncbi.nlm.nih.gov/29154054/

[23] https://www.nhs.uk/conditions/vitamins-and-minerals/vitamin-b/

[24] https://www.healthline.com/health/food-nutrition/is-silicon-dioxide-in-supplements-safe#TOC_TITLE_HDR_1